In a significant advancement for the fields of hematology and spatial biology, scientists at the Indiana University School of Medicine…
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Bioengineered Bone Marrow-on-a-Chip Platform Revolutionizes Human Hematopoiesis Research and Drug Toxicity Screening
The human bone marrow is a complex, sequestered organ that serves as the primary engine for the body’s circulatory and…
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Glioblastoma Research Reveals Systemic Impact on Skull Bone and Immune Function
Researchers from the Montefiore Einstein Comprehensive Cancer Center (MECCC) and the Albert Einstein College of Medicine have fundamentally challenged the…
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Inflammatory Remodeling of the Bone Marrow Niche: New Insights into the Early Drivers of Clonal Hematopoiesis and Myelodysplastic Syndrome
The human bone marrow serves as a prolific biological factory, generating millions of new blood and immune cells every second…
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Scientists Replicate Human Bone Marrow Architecture Using Only Human Cells to Advance Blood Cancer Research and Reduce Animal Testing
The human bone marrow is often described as the body’s primary "blood factory," a highly sophisticated and specialized tissue responsible…
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A GLP-1 bone study shows why matching matters in real-world evidence
The burgeoning field of real-world evidence (RWE) is transforming how medical professionals and regulators understand the long-term effects of therapeutics,…
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HKU Researchers Identify Molecular Exercise Sensor Piezo1 as Key to Preventing Osteoporosis and Bone Loss
Researchers from the Department of Medicine at the School of Clinical Medicine, LKS Faculty of Medicine, University of Hong Kong…
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Breast cancers that disseminate to bone marrow acquire aggressive phenotypes through CX43-related tumor-stroma tunnels.
A collaborative study conducted by researchers at the University of Michigan and the University of California San Diego has identified…
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Molecular Switch Discovery Enhances Blood Stem Cell Activation for Advanced Bone Marrow Transplants and Gene Therapies
A breakthrough preclinical study led by investigators at Weill Cornell Medicine has identified a singular molecular switch, known as FLI-1,…
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Discovery of Fam102a as a Dual Regulator in Bone Remodeling Offers New Pathway for Osteoporosis Treatment
The landscape of regenerative medicine and endocrinology has shifted following the landmark identification of a novel protein that serves as…
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